Purpose

We reviewed the effects of obesity and long-term weight loss on nononcological urological disease, particularly urinary stone formation, erectile dysfunction, female sexual dysfunction, voiding dysfunction and urinary incontinence.

Materials and ...

Purpose

Nephron sparing surgery is an increasingly used alternative to Robson's radical nephroadrenalectomy. The indications for adrenalectomy in patients undergoing partial nephrectomy are not clearly defined and some surgeons perform it routinely for ...

Purpose

We evaluated the effect of warm ischemia time on early postoperative renal function following laparoscopic partial nephrectomy.

Materials and Methods

Of 453 patients who were surgically treated for renal tumors between May 2001 and September 2007,...

Purpose

We evaluated the additional usefulness of multiphase computerized tomography for improving the differential diagnosis of cystic renal masses by the Bosniak classification.

Materials and Methods

We reviewed the records of 104 patients with Bosniak ...

Purpose

The goals of surgery for renal tumors include the preservation of renal function. When considering surgical options, it is important to accurately assess renal function and the risk of postoperative chronic kidney disease.

Materials and Methods

...

Purpose

Treatment options in patients with renal cell carcinoma have changed in recent years. However, few studies include detailed information on patient, clinical and health system characteristics in the evaluation of surgical management and the use of ...

Purpose

Pancreatic metastasis accounts for 2% of metastatic renal cell carcinoma cases. Surgical management is typically recommended because of the limited value of immunotherapy as an effective treatment. Sunitinib recently showed clinical efficacy in ...

Purpose

We conducted a phase II trial of neoadjuvant paclitaxel, carboplatin and gemcitabine as well as transurethral resection of bladder tumor to evaluate the clinical T0 (cT0) rate with paclitaxel, carboplatin and gemcitabine, and to study cystoscopic ...

Purpose

We examined the impact of lymphadenectomy on the clinical outcomes of patients with upper tract urothelial cancer treated with radical nephroureterectomy.

Materials and Methods

Data were collected on 1,130 consecutive patients with pT1-4 upper ...

Purpose

Studies suggest that patients who undergo thorough lymphadenectomy for bladder cancer benefit from improved survival. We evaluated the incidence of and trends in lymphadenectomy in conjunction with radical cystectomy for bladder cancer.

Materials ...

Purpose

Recent studies have identified 2 distinct genetic variants along chromosome 17, including allele T of single nucleotide polymorphism rs4430796 on 17q12 and allele G of single nucleotide polymorphism rs1859962 on 17q24, that have been linked to ...

Purpose

Most men with increased serum prostate specific antigen and negative biopsy require repeat biopsy because of the lack of a sensitive and specific prostate cancer detection test. In this study we evaluated the diagnostic potential of a duplex ...

Purpose

The Prostate Cancer Prevention Trial reported that 15% of men with a prostate specific antigen less than 4 ng/ml and a normal digital rectal examination have biopsy detectable prostate cancer. However, limited published data describe the tumor ...

Purpose

We determined the clinical significance of prostate specific antigen half-time and prostate specific antigen doubling time after the prostate specific antigen nadir as predictors of the response to androgen deprivation therapy for metastatic ...

Purpose

We determined outcomes in patients with testicular cancer with large volume (greater than 10 cm) retroperitoneal teratoma treated with post-chemotherapy retroperitoneal lymph node dissection.

Materials and Methods

A retrospective review of our ...

Purpose

Post-void residual urine can lead to various complications, including urinary tract infection. Recently investigators calculated that a cutoff value of 180 ml has considerably high sensitivity and specificity for significant bacteriuria in ...

Purpose

We determined the functional consequences of urinary tract infection in patients with an ileal bladder substitute in terms of urinary continence, post-void residual and urinary retention.

Materials and Methods

A total of 48 patients with culture ...

Purpose

In this study we identify the characteristics of the urodynamic results in patients with painful bladder syndrome/interstitial cystitis and in those with idiopathic overactive bladder.

Materials and Methods

The fluoroscopic urodynamic study ...

Purpose

We conducted a retrospective analysis to determine associations among symptoms, sleep disturbances and quality of life in responder and nonresponder groups of patients with interstitial cystitis.

Materials and Methods

Patients in a multidose ...

Purpose

Recent studies have suggested a defect in phosphate balance as a significant underlying cause of calcium urolithiasis. In this study we assessed the influence of decreased renal phosphate reabsorption capacity on urinary metabolic abnormalities ...

Purpose

Recent studies have demonstrated that mineral and electrolyte abnormalities develop in patients who undergo bariatric surgery. While it is known that these abnormalities are a risk factor for urolithiasis, the prevalence of stone disease after ...

Purpose

We assessed the near term comfort of newly designed ureteral study stents or marketed control stents, including Polaris^™ and Percuflex® stents. Study stents had distal 6Fr pigtail ends with 3Fr or less loops. Decreased material in situ was ...

Purpose

We measured patient reported bother due to overactive bladder syndrome, patterns of physician consultation and prescription medication use for overactive bladder symptoms in adults in the United States.

Materials and Methods

A survey sample was ...

Purpose

We assessed the effect of tolterodine extended release plus behavioral intervention on treatment satisfaction and bladder diary variables in patients with overactive bladder who had been previously treated and were dissatisfied with tolterodine ...

Purpose

We determined the effectiveness of cystoscopic administration of botulinum-A toxin compared to placebo for the treatment of urinary incontinence in subjects with idiopathic overactive bladder.

Materials and Methods

Subjects were recruited from ...

Purpose

To mitigate TOT® complications we designed a modified TOT technique called canal TOT. We describe this new technique and evaluate its feasibility.

Materials and Methods

Between October 2006 and June 2007, 105 consecutive women with stress urinary ...

Purpose

The introduction of the artificial urinary sphincter represented a significant advance in treating urinary incontinence. We examined temporal trends in artificial urinary sphincter use, focusing on adoption of the device with time, individual ...

Purpose

We assessed the use of urethral pressure reflectometry in detecting pressure increases in the female urethra and compared the usefulness of urethral pressure reflectometry vs urethral pressure profilometry in a pharmacodynamic intervention study.

...

Purpose

We evaluated the efficacy and safety of silodosin for treatment of benign prostatic hyperplasia symptoms in 2 randomized, placebo controlled, phase 3 studies.

Materials and Methods

Men 50 years or older with an International Prostate Symptom ...

Purpose

We sought to predict the duration of urinary incontinence after radical prostatectomy based on potential risk factors.

Materials and Methods

We included 104 patients after radical retropubic prostatectomy at University Hospital Gasthuisberg, ...

Purpose

This study tested whether individuals with at least 1 copy of the short (S) or long (L)_G allele of the serotonin transporter gene-linked polymorphic region exhibit a greater incidence of premature ejaculation compared with L_AL_A individuals.

...

Purpose

A total of 537 urology residents participated in a randomized trial of on-line spaced education in 2005 that used 96 American Urological Association Self-Assessment Study Program questions as educational material. I investigated whether the ...

Purpose

The primary responsibility of institutional review boards is to protect human research subjects and, therefore, ensure that studies are performed in accordance with a standard set of ethical principles. A number of groups have compared the ...

Purpose

Vesical stones are common in children in developing countries. Cystolithotomy is the traditional treatment but a percutaneous approach has been advocated. The aim of this study was to evaluate retrospectively our experience with percutaneous ...

Purpose

In rare instances when native bladder tissue is either unsuitable or unavailable a continent neobladder may be an option for pediatric lower urinary tract reconstruction. We report our long-term outcomes and experience in this challenging patient ...

Purpose

Dextranomer/hyaluronic acid implantation is associated with a granulomatous inflammatory reaction, replaced by fibrosis. Appearance of myofibroblasts is considered a crucial event in fibrosis, and CD68 positive cells and other factors are implied ...

Purpose

Endoscopic treatment of vesicoureteral reflux has gained popularity and is frequently used as a first-line therapy. Reports of potential long-term complications from this treatment modality are lacking. We review the development of mound ...

Purpose

We compared 2 cohorts of children with neurogenic urinary incontinence undergoing bladder neck sling with and without augmentation to determine relative continence outcomes, catheterization intervals, anticholinergic requirements and health ...

Purpose

The major indication for adolescent left varicocelectomy is testicular asymmetry. However, a period of observation is often recommended preoperatively to determine if the asymmetry resolves, persists or progresses. We investigated whether ...

Purpose

We systematically reviewed the results of varicocelectomy by Palomo procedure in children and adolescents.

Materials and Methods

We performed a search of the English literature through the MEDLINE^® database and the Cochrane Central Search ...