Purpose

With current diagnostic modalities the proportion of patients diagnosed with idiopathic hemospermia has decreased dramatically. The dilemma now is how far to investigate these patients since in the majority it is a benign and self-limiting ...

Purpose

We systematically reviewed the literature on the effectiveness, durability and safety of the UroLume^™ stent for men with benign prostatic hyperplasia.

Materials and Methods

We searched the MEDLINE® and EMBASE^™ databases for 1989 to 2005. ...

Purpose

The genitals are at the forefront of evolution. Advantageous features of genital form and function determine which individuals pass their genes to future generations. The male genitalia are primarily for sperm deposition but additional functions ...

Purpose

This review is of the events that led up to the discovery of the cavernous nerves and the development of nerve sparing radical retropubic prostatectomy.

Materials and Methods

The correspondence between Pieter J. Donker and Patrick C. Walsh, along ...

Purpose

While there are data available indicating the incidence and prevalence of bladder and upper tract urothelial cancer, population level data on resource use, costs and patterns of care for these cancers are limited. We quantified the economic ...

Purpose

We quantified the burden of cryptorchidism and hypospadias in the United States by identifying trends in the use of health care resources and estimating the economic impact of the disease.

Materials and Methods

The analytical methods used to ...

Purpose

We quantified the burden of ureteropelvic junction obstruction in the United States by identifying trends in the use of health care resources and estimating the economic impact of the disease.

Materials and Methods

The analytical methods used to ...

Purpose

We quantified the burden of vesicoureteral reflux and ureteroceles in the United States by identifying trends in the use of health care resources and estimating the economic impact of the diseases.

Materials and Methods

The analytical methods ...

Purpose

The incidence of urethral stricture disease in the United States is unknown. We estimated the impact of urethral stricture disease by determining its prevalence, costs and other measures of burden, including side effects and the need for surgical ...

Purpose

Male sexual health has taken on increased importance as the United States population ages, develops coexisting medical conditions and undergoes interventions that can affect sexual function. We characterized the burden and severity of disease, ...

Purpose

Renal cell carcinoma invading the perinephric fat is classified as a stage T3a tumor in the 2002 TNM version. Based on long-term followup we examined the prognostic significance of this definition.

Materials and Methods

We evaluated the outcome ...

Purpose

We determined the impact of clinical and pathological factors in the outcome of patients with renal cell carcinoma treated surgically.

Materials and Methods

We retrospectively reviewed the records of 230 consecutive patients after radical or ...

Purpose

Active surveillance of small incidental renal masses is associated with slow radiographic growth and a low risk of metastatic progression. Radiographic tumor size, in the absence of histological data, is the only prognostic indicator available ...

Purpose

Collecting duct carcinoma of the kidney is a rare and aggressive neoplasm of the distal collecting tubules for which there is no established treatment. Since the histology of collecting duct carcinoma is similar to that of urothelial carcinoma, ...

Purpose

We prospectively evaluated long-term survival in patients with renal cell carcinoma extending to the inferior vena cava.

Materials and Methods

From 1993 and thereafter we followed 86 men and 48 women with a median age of 64 years (range 28 to 86) ...

Purpose

We determined the frequency and predictors of complications of partial and total nephrectomy in a population based sample.

Materials and Methods

There were 3,019 partial and 18,575 total nephrectomies identified from the Nationwide Inpatient ...

Purpose

Urothelial carcinoma is a disease of the entire urothelium. Recent molecular insights suggest that the biology of some upper urinary tract and bladder urothelial carcinoma differ. These differences may affect tumor phenotype. Observational ...

Purpose

Endoscopic management of renal pelvis and ureteral urothelial carcinoma is gaining acceptance as a conservative treatment modality. Patients with a history of bladder urothelial carcinoma are at high risk for upper tract recurrence. We evaluate ...

Purpose

The standard approach to treatment for patients with high risk Ta, Tis, or T1 bladder cancer that persists or recurs after bacillus Calmette-Guerin is radical cystectomy in medically fit patients. Maintenance bacillus Calmette-Guerin has been ...

Purpose

Early prostate cancer antigen is a nuclear matrix protein that was recently shown to be expressed in prostate adenocarcinoma and adjacent benign tissue. Previous studies have demonstrated early prostate cancer antigen expression in benign ...

Purpose

Percent free prostate specific antigen and prostate specific antigen density have been independently shown to increase the specificity of prostate cancer screening in men with prostate specific antigen levels between 4.1 and 10.0 ng/ml. Recent ...

Purpose

We previously reported that the median prostate specific antigen for men 40 to 49 years old is 0.7 ng/ml and that a baseline prostate specific antigen between 0.7 and 2.5 ng/ml is associated with a 14.6-fold increased risk of prostate cancer. ...

Purpose

Men undergoing screening for prostate cancer are recommended to undergo digital rectal examination and prostate specific antigen measurement. We previously presented data from the Prostate Cancer Prevention Trial indicating that finasteride ...

Purpose

About 15% of men experience prostate specific antigen recurrence after radical prostatectomy. A DNA methylation based molecular test could provide important information to predict which patients are most likely to experience recurrence.

Materials ...

Purpose

We describe biopsy results in patients with prostate cancer treated with brachytherapy.

Materials and Methods

A total of 1,562 men with localized prostate cancer were treated with permanent prostate brachytherapy, of whom 508 agreed to ultrasound ...

Purpose

Patients with a high body mass index, previous pelvic surgery or large prostate size are not considered ideal candidates for radical prostatectomy. We assessed the impact of body mass index, previous pelvic surgery and prostate weight on ...

Purpose

We assessed the impact of tumor volume, tumor volume ratio (tumor volume-to-prostate volume), surgical experience and type of nerve sparing procedure on biochemical recurrence after laparoscopic radical prostatectomy.

Materials and Methods

Of 1,...

Purpose

Patients with adverse pathological features are at high risk for recurrence following radical prostatectomy. To improve outcomes in this population we performed a phase II study of adjuvant docetaxel in these high risk patients.

Materials and ...

Purpose

Percutaneous nephrolithotomy is a commonly used procedure for treatment of large or complex renal calculi. In some instances postoperative residual stone fragments are an unavoidable result. Yet to our knowledge no study has examined the impact ...

Purpose

Bowel function may be disturbed after intestinal segments are transposed into the urinary tract to reconstruct or replace the bladder. In 1997 our group was the first to report major bowel dysfunction in a cohort of such patients. Up to 42% of ...

Purpose

We present a technique not previously described for proximal bulbous or bulbomembranous urethral reconstruction of excision and primary anastomosis. The technique has the potential advantages of preserving the proximal urethral blood supply.

...

Purpose

We report our experience and long-term followup of patients undergoing excision and primary anastomotic reconstruction for anterior urethral strictures.

Materials and Methods

From July 1986 to May 2006 the charts of 260 patients who underwent ...

Purpose

We assessed the relationships among severity measures of urinary incontinence in women with stress predominant symptoms enrolled in a randomized clinical trial comparing 2 surgical techniques (Burch colposuspension vs pubovaginal sling) for ...

Purpose

We determined the prevalence of symptoms suggestive of chronic pelvic pain syndrome in an urban population and assessed associations with lower urinary tract symptoms and erectile dysfunction.

Materials and Methods

Men participating in a ...

Purpose

We compared the exclusion rate for potential living renal donors evaluated with computerized tomography angiography and radionuclide renal scintigraphy (renal scan) vs excretory urogram, renal scan and renal arteriography.

Materials and Methods

...

Purpose

Interstitial cystitis significantly negatively impacts quality of life. The demographic and clinical factors associated with decreased quality of life in these patients have not been well studied.

Materials and Methods

Women with moderate/severe ...

Purpose

An experienced urology nurse observed that patients seemed to tolerate the procedure better when allowed to see the monitor in real time during office based cystoscopy. We assessed the impact of this on visual analog scale pain scores.

Materials ...

Purpose

The relationship between urinary incontinence and race/ethnicity is poorly understood. We analyzed Medicare claims data to identify racial differences in the diagnosis, treatment and outcomes of women with stress urinary incontinence.

Materials ...

Purpose

We identified sociodemographic characteristics that predict poor disease understanding in low income, uninsured men with prostate cancer.

Materials and Methods

A total of 399 low income, uninsured men with prostate cancer participating in the Men’...

Purpose

Health related quality of life in Japanese men with localized prostate cancer treated with current multidisciplinary treatment modalities was assessed using a newly developed Japanese version of the Extended Prostate Cancer Index Composite. We ...

Purpose

Urachal remnants are generally treated with the open method. We evaluated the role of laparoscopy for this anomaly in a consecutive series of 27 children treated during a 12-year period.

Materials and Methods

A total of 27 children with a median ...

Purpose

We retrospectively compared morbidity and success rates in children who underwent percutaneous nephrolithotomy with 3 different sizes of instruments.

Materials and Methods

Percutaneous nephrolithotomy was performed using adult instruments via a ...

Purpose

We present the long-term results of our experience with application of tissue expanders for phallic reconstruction in patients with a history of multiple surgical repairs.

Materials and Methods

We retrospectively reviewed the medical records of ...

Purpose

We assessed the feasibility of pediatric redo laparoscopic pyeloplasty in comparison to redo open pyeloplasty for safety, efficacy, operative time, blood loss, postoperative analgesic requirements, length of hospitalization, complications, need ...

Purpose

Urinary tract infection remains a major cause of morbidity in pediatric renal transplant recipients. In otherwise healthy children bladder dysfunction increases the susceptibility to urinary tract infection. The aims of this study were to ...

Purpose

TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) triggers apoptosis in various tumor cells by engaging death receptors 4 and 5. We investigated the effect of chemotherapeutic agents on death receptor 4 mediated apoptosis in human ...

Purpose

Intravesical adenovirus mediated interferon-α gene transfer has a potent therapeutic effect against superficial human bladder carcinoma xenografts growing in the bladder of athymic nude mice. We determined whether the inhibition of angiogenesis ...

Purpose

We developed and describe a practical method by which primary prostate cancer specimens can be screened for recurrent chromosomal translocations, which is a potential source of fusion genes, as well as a process by which identified translocations ...

Purpose

Cyclooxygenase-2 functions as a survival factor by protecting cells from apoptosis. We analyzed cyclooxygenase-2 expression in LNCaP-COX-2 and LNCaP-Neo cell lines treated with irradiation.

Materials and Methods

LNCaP-COX-2 and LNCaP-Neo cells ...