Purpose

A contemporary review of the indications, techniques and outcomes is presented for nephron sparing approaches to solid renal masses, emphasizing their role for the treatment of renal cell carcinoma. We also reviewed the evolving role of minimally ...

Purpose

We evaluate the outcome in patients with node positive bladder cancer with particular reference to the effect of individual characteristics of positive nodes on survival after meticulous pelvic lymphadenectomy at cystectomy.

Materials and Methods

Purpose

We investigated the relationship of long-term pancreatic hormone hypersecretion with adrenal lesions in patients with multiple endocrine neoplasia type 1 and in those with sporadic pancreatic endocrine tumors.

Materials and Methods

We assessed ...

Purpose

We developed a real-time tracking system for renal stones that decreases the number of shock waves and treatment time of shock wave lithotripsy.

Materials and Methods

Ultrasound images were analyzed to identify the renal stones. A computer ...

Purpose

We compared the long-term impact on renal function after shock wave lithotripsy, percutaneous nephrolithotomy or the 2 techniques combined in patients with a solitary kidney.

Materials and Methods

A total of 45 women and 38 men 15 to 86 years old ...

Purpose

Laparoscopic adrenalectomy has become an effective option for removing small adrenal tumors. We evaluated the retroperitoneal approach with regard to operative complications, morbidity and hospital stay.

Materials and Methods

Between January 1995 ...

Purpose

The laparoscopic technique for bilateral nephrectomy in patients with autosomal dominant polycystic kidney disease is technically difficult. The procedure may be more acceptable if alterations to the technique made it safer and easier to perform. ...

Purpose

We assessed the feasibility, reproducibility and morbidity of retroperitoneal laparoscopic pyeloplasty for ureteropelvic junction obstruction.

Materials and Methods

A total of 55 retroperitoneal laparoscopic pyeloplasties were performed at 3 ...

Purpose

Laparoscopic management of ureteral pathologies, such as ureteropelvic junction obstruction, ureteral calculi and retroperitoneal fibrosis, has proved to be highly effective. We present our initial experience with the laparoscopic Boari flap in ...

Purpose

We analyzed the effects of the change in TNM classification from the 1987 to the 1997 version and suggest a modified tumor size cutoff point between T stages 1 and 2 for renal cell carcinoma.

Materials and Methods

We evaluated a database ...

Purpose

Ipsilateral adrenalectomy is usually performed during radical nephrectomy because of renal cell cancer. Because renal tumors are detected more often in the earlier stages due to widespread use of ultrasound and computerized tomography, we define ...

Purpose

Few published studies have combined prognostic factors to predict the likelihood of recurrence after surgery for renal cell carcinoma. We developed a nomogram for this purpose.

Materials and Methods

With Cox proportional hazards regression ...

Purpose

Patients with metastatic renal cell carcinoma have a reported 5-year survival of 0% to 20%. The ability to predict which patients would benefit from nephrectomy and interleukin-2 (IL-2) therapy before any treatment is initiated would be useful ...

Purpose

While detecting bladder cancer, bladder tumor markers demonstrate improved sensitivity compared with urinary cytology but the current limitation is the low specificity and positive predictive value, that is high false-positive rate. We examined ...

Purpose

It is not uncommon for a locally advanced, nonurological malignancy to invade the bladder. Partial cystectomy may be required to ensure complete tumor eradication. To our knowledge the true benefit of this procedure is unknown.

Materials and ...

Purpose: Transrectal ultrasound guided biopsy of the prostate is the most common modality used to diagnose prostate cancer. Although many biopsy protocols have been described, in our opinion the role of enema before biopsy has not been definitively ...

Purpose

We hypothesized that markedly increasing the number of cores obtained during prostate needle biopsy may improve the cancer detection rate in men with persistent indications for repeat biopsy.

Materials and Methods

We performed saturation ...

Purpose: The free-to-total prostate specific antigen (PSA) ratio and complexed PSA have been introduced as adjuncts to total PSA for prostate cancer screening. Little data exist on the use of these tests for serial PSA screening. We compared serial total ...

Purpose

Agent Orange, a chemical that was widely used in the Vietnam War as a defoliant, is widely accepted as a health hazard but its potential causative role in prostate cancer has been controversial. We evaluated the rate of prostate cancer in ...

Purpose

Because of the recent increase in nonpalpable prostate cancer (clinical stage T1c) in men, preoperative needle biopsy findings have had an important role for treatment decisions. We examine the correlation among histopathological features of 6 ...

Purpose

External beam radiotherapy may be given after radical prostatectomy as adjuvant (immediate) or therapeutic (delayed) treatment, the latter in response to evidence of disease recurrence. In patients receiving delayed radiotherapy the necessity of ...

Purpose: Patients with surgically staged localized prostate cancer treated with external beam radiation therapy were retrospectively analyzed for 15 and 20-year overall and cause specific survival. The need for additional therapy was also evaluated....

Purpose

Because of the morbidity associated with missed ureteral injuries, a high index of suspicion must be present to diagnose this type of injury. We reviewed our 40 years of trauma experience at Grady Memorial Hospital.

Materials and Methods

We ...

Purpose

We determined whether genetic material is present in the commercially processed cadaveric allografts used in sling surgery.

Materials and Methods

We evaluated 16 samples from 2 commercial sources of human allograft, including 8 each of freeze-...

Purpose

We investigated the interexaminer reliability of transrectal ultrasound measurement of total prostate and transition zone volume among 3 examiners with various levels of experience.

Materials and Methods

A total of 121 patients 39 to 82 years old ...

Purpose

We compared the safety and patient acceptance of a conventional Nélaton and a prelubricated nonhydrophilic catheter in 18 spinal cord injured patients on intermittent catheterization.

Materials and Methods

In a prospective crossover study each ...

ABSTRACT

Purpose

Interstitial cystitis is a disorder of the bladder characterized by urgency and frequency of urination, and pelvic pain. The classic type of interstitial cystitis is characterized by Hunner’s ulcers, which are focal regions of severe ...

ABSTRACT

Purpose

Spermatoceles are commonly treated with open surgical ablation. With the increasing shift towards minimally invasive surgery and heightened awareness, both patient and surgeon accept and prefer the less intrusive approach. Treatment of ...

Purpose

We compared the short-term efficacy, safety and tolerability of transdermal versus oral oxybutynin in adults with urge urinary incontinence.

Materials and Methods

Volunteers with detrusor instability currently responding to oral immediate release ...

Purpose

Management of idiopathic detrusor instability is difficult in most patients mainly due to the lack of a complete understanding of the pathophysiology. Oxybutynin and transcutaneous electrical nerve stimulation have been used but to our knowledge ...

Purpose

The anatomical and functional results of pubovaginal sling procedure using polypropylene mesh were investigated.

Materials and Methods

A total of 50 women with stress urinary incontinence, including 26 with type 2, 7 with mixed type 2/3 and 17 ...

Purpose

Bladder outlet obstruction secondary to benign prostatic hyperplasia (BPH) is the most common diagnosis in older men with lower urinary tract symptoms. However, these symptoms also can occur with interstitial cystitis. We determine whether the ...

Purpose

We studied the association between smoking habits and absorption during transurethral prostatic resection in healthy patients, and in those with medical disease and prostate cancer.

Materials and Methods

Smoking habits and the presence of medical ...

Purpose

Transurethral resection of the prostate is the standard operation for acute urinary retention, although laser prostatectomy is reportedly effective and safe. The ClasP (conservative management, laser, transurethral resection of the prostate) ...

Purpose

We investigate the safety and efficacy of suprapubic transvesical prostatectomy, and the change in bladder wall thickness after surgery.

Materials and Methods

We conducted a prospective 1 center study of 32 consecutive patients who underwent ...

Purpose

Because a pregnancy can be achieved without a male infertility evaluation, some have questioned its usefulness. However, by bypassing a urological evaluation the man might not learn the cause of infertility and not be offered specific corrective ...

Purpose

Of the various methods of hemodynamic studies performed to evaluate erectile dysfunction penile color Doppler ultrasound is currently considered the best. However, intracavernous injection is invasive and has adverse effects, such as prolonged ...

Purpose

Penile curvature due to Peyronie’s disease is often treated with plaque incision or excision and grafting. The advantages of various graft materials have long been debated. We studied the outcomes of dermal and cadaveric pericardial grafts after ...

Purpose

We analyzed the practice of mandatory surgical intensive care unit admission after radical cystectomy, and defined objective criteria to predict active treatment requirements and surgical intensive care unit stay.

Materials and Methods

We ...

Purpose

Minor hemorrhage during laparoscopic procedures may obscure the operative field. We describe the use of an especially designed, 4 × 4 absorbent sponge for multiple laparoscopic applications.

Materials and Methods

The cigarette sponge, also known ...

Purpose

Intracorporeal knot tying in laparoscopic surgery is time-consuming and difficult to learn. We present a new technique, that we call the pre-looped intracorporeal knot technique, which obviates the difficulties and saves time.

Materials and ...

Purpose

Minimally invasive surgical approaches to renal and adrenal tumors have gained increasing use. The addition of robotic assistance and mechanical devices has decreased the number of assistants required for these often long cases. We describe an ...

Purpose

The feasibility and safety of remote laparoscopic surgery using a surgical telemanipulator have been demonstrated in laboratory experience and recently in clinical practice. To our knowledge we report the first robot assisted, laparoscopic ...

Purpose

We describe technical considerations of the laparoscopic repair of a renal artery aneurysm.

Materials and Methods

A 57-year-old woman presented with a 3 cm. aneurysm of the distal left main renal artery at its bifurcation. Using a purely ...

Purpose

When using a ureteral access sheath following a ureteroscopic procedure, placement of an internal ureteral stent can be simplified by inserting the stent through the sheath without the need to reinsert the cystoscope.

Materials and Methods

An ...

ABSTRACT

Purpose

To our knowledge despite numerous studies the biological effect of extracorporeal shock wave lithotripsy (ESWL, Dornier Medical Systems, Inc., Marietta, Georgia) on the function of the immature kidney has not yet been evaluated. We ...

ABSTRACT

Purpose

We have previously defined the anatomy of the neurovascular bundle in the normal and hypospadiac penis. These studies were based on analysis of the fetal penis distal to the pubic arch without total inclusion of the crural bodies. To our ...

ABSTRACT

Purpose

We describe the presenting symptoms, evaluation and natural history of urethrorrhagia in boys.

Materials and Methods

The records of 27 consecutive toilet trained boys with idiopathic urethrorrhagia were retrospectively reviewed for ...

ABSTRACT

Purpose

We present a modified technique of pyeloplasty that seems ideally suited for reoperative as well as primary repair of ureteropelvic junction obstruction due to high ureteral insertion.

Materials and Methods

This repair combines the ...

ABSTRACT

Purpose

We determined whether testicular size at orchiopexy is predictive of fertility potential and whether size correlates with sperm parameters, hormone levels or testicular volume in adulthood.

Materials and Methods

Testicular size obtained ...

Purpose

We determined parental preferences for the treatment of vesicoureteral reflux in their child.

Materials and Methods

Parents of children with vesicoureteral reflux were prospectively recruited to evaluate choices in reflux management. In each case ...

Purpose

To verify in an experimental model whether gastrocystoplasty may protect patients with chronic renal failure from acid loading associated acidosis a wedge-shaped portion of the middle stomach was used to improve bladder capacity in animals with ...

Purpose

To our knowledge innervation of the upper urinary tract and its role in motility and sensation are not clearly understood. The whole mount preparation technique provides 3-dimensional (D) morphology of the innervation and its relationship of ...

Purpose

We created viable bladder tissue by transplantation with immunosuppression.

Materials and Methods

For bladder transplantation the bladder of newborn Brown-Norway rats was excised and each was transplanted into a pouch created in the distal ...

Purpose

An increased risk of nephrolithiasis has been associated with the ingestion of grapefruit juice in epidemiological studies. To our knowledge the basis of this effect of grapefruit juice has not been studied previously. We studied the effect of ...

Purpose

Bikunin is a Kunitz-type protease inhibitor found in serum and urine. It has been implicated in urinary stone formation. This study was designed to investigate the role of urinary bikunin in stone formation.

Materials and Methods

Urinary ...

Purpose

Hyperoxaluria is a recognized cause of tubulointerstitial lesions and it may contribute to chronic renal failure. In previous studies we demonstrated that enalapril was effective against the progression of tubulointerstitial lesions in a 4-week ...

Purpose

Few studies have evaluated the effect of radiofrequency thermal ablation on renal tissue, although it has been used clinically to treat small renal masses. We studied the size and histology of lesions created with radiofrequency thermal ablation ...

Purpose

We present our technique of laparoscopic ileal conduit creation after cystoprostatectomy in a porcine model performed in a completely intracorporeal manner.

Methods and Methods

After developing the technique in 5 acute animals laparoscopic ...

Purpose

We determined the feasibility of a percutaneous approach using magnetic resonance imaging (MRI) for creating cryoablation lesions in the porcine kidney.

Methods and Methods

Three domestic swine underwent renal cryoablation under MRI guidance with ...

Purpose

Incidentally detected small renal tumors appear to grow slowly and be localized to the kidney. Minimally invasive therapies are being investigated as alternatives to standard surgical techniques. Radiofrequency ablation has been reported for the ...

Purpose

Effector T cell populations generated using 2 methods of in vitro activation are currently being tested in separate clinical trials as immunotherapy for patients with advanced cancer, including renal cell carcinoma. To determine the most ...

Purposes

The nature of p53 mutation has been reported to affect cellular responses to chemotherapy. We characterized the impact of p53 mutations on drug resistance in bladder cancer cells.

Methods and Methods

Various human p53 mutants (V143A, V173L, ...

Purpose

We examined the changes in the lower urinary tract after delivery, intravaginal ballooning and/or ovariectomy.

Materials and Methods

The study included 10 virgin and 48 primiparous pregnant rats. Cystometry and the stress/sneeze test were ...

Purpose

We determined the sites of the antinociceptive action of morphine in the experimental model of cyclophosphamide induced cystitis and investigated the afferent nerve fibers involved in nociception transmission originating from the bladder.

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