Abstract

The kidney stone-forming risk of a high sodium diet was evaluated by assessing the effect of such a diet on the crystallization of stone-forming salts in urine. Fourteen normal subjects participated in 2 phases of study of 10 days duration each, ...

Abstract

Between April 1991 and February 1992 we obtained 87 percutaneous core needle biopsy specimens from 60 patients with the automatic biopsy gun. In 78 cases (89.7%) enough renal tissue was obtained for histological analysis. Acute rejection was ...

Abstract

Lymphoceles are among the most frequent surgical complications after renal transplantation. We performed laparoscopic drainage in 5 patients with a large lymphocele in the small pelvis after successful kidney transplantation.

Abstract

Between 1975 and 1991, 142 patients with renal cell carcinoma and 10 with oncocytoma underwent a total of 164 kidney preserving operations. The indication for surgery was imperative (group 1, 47 patients) among those with a solitary kidney (9), ...

Abstract

The use of topical agents in the treatment and prophylaxis of transitional cell carcinoma of the bladder is well described. Several physicians have reported the use of these materials in the upper urinary tract for treatment of transitional cell ...

Abstract

With the current practice of continent urinary diversion the patient still has a cutaneous stoma and must perform intermittent catheterization. To circumvent these problems we devised the uretero-ileoceco-proctostomy (ileocecal rectal bladder), in ...

Abstract

From May 1988 through May 1991, 14 patients with radiation-induced hemorrhagic cystitis confirmed by cystoscopy and biopsy, who had failed all other attempts at management and who had no evidence of infection or recurrent malignancy, were treated ...

Abstract

We describe the use of lidocaine as a topical anesthetic for 35 patients undergoing random bladder biopsies (bladder mappings) and cold-cup resection of small bladder lesions. Serum lidocaine levels were measured 7 to 10minutes after instillation ...

Abstract

Postoperative urethral strictures following extracorporeal circulation in open heart surgery are not uncommon. The etiology is not clear. Ischemia and pressure of the Foley catheter may cause a lesion that eventually leads to urethral stricture. ...

Abstract

Since 1974, 71 female patients between 3 and 25 years old have undergone implantation of the artificial urinary sphincter for treatment of urinary incontinence. Of these women 9 have become pregnant and delivered 11 normal children. In 2 women the ...

Abstract

Objective determination of spermatogenesis has been accomplished by quantitative testicular biopsy, which, although laborious, has served as the standard for spermatogenic assessment. Aspiration deoxyribonucleic acid (DNA) flow cytometry of the ...

Abstract

Evaluation and management services provided by the practicing urologist have changed dramatically during the last few years. This is particularly evident in the approach to men with bladder outlet symptoms and in those in whom the diagnosis of ...

Abstract

In previous studies the severity of symptoms of prostatism in men with benign prostatic hyperplasia have not correlated well with prostate size, degree of bladder trabeculation, uroflowmetry or post-void residual volume. As part of a prospective ...

Abstract

Several physicians have used luteinizing hormone-releasing hormone agonists for small, selected groups of patients with benign prostatic hyperplasia but their clinical role in this indication is still not well defined. We investigated the effect ...

Abstract

Neuroendocrine cells have been reported in up to 50% of all prostatic adenocarcinomas. These cells appear to influence the prognosis of these tumors. The distribution of the neuroendocrine cell population in the normal prostate gland, through all ...

Abstract

The prostate specific antigen (PSA) level has become an important but imperfect means of detecting prostatic carcinoma. PSA index (serum PSA normalized to estimated gland volume) has been suggested to improve the performance characteristics of PSA ...

Abstract

Prostate specific antigen (PSA) determinations after radical prostatectomy are valuable in detecting persistent disease. Previously, we determined that 0.4ng./ml. PSA was a reliable clinical threshold using the Hybritech Tandem-R PSA assay. ...

Abstract

The incidence of clinically detected prostate cancer is increasing with more frequent diagnosis in younger male patients. Whether this represents a genuine increase in incidence or earlier detection is not clear. To understand better the evolution ...

Abstract

Prior studies have evaluated high grade prostatic intraepithelial neoplasia on biopsy material when undiagnosed carcinoma or benign prostatic hyperplasia (BPH) may have been associated with elevated serum prostate specific antigen (PSA) levels. We ...

Abstract

A total of 111 patients with clinically localized prostate cancer (stage A or B) underwent endorectal surface coil magnetic resonance imaging (MRI) for preoperative staging of the disease. Of the patients 43 with advanced disease on endorectal ...

Abstract

The operative morbidity and convalescence of our initial 30 patients who underwent laparoscopic pelvic lymph node dissections were compared to those of 16 patients who underwent open surgical pelvic lymph node dissections performed at our ...

Abstract

We studied 98 patients with locally confined but lymph node positive prostatic cancer (1 stage T1, 29 stage T2, 55 stage T3 and 2 stage T4) who were not treated by radical prostatectomy. A retrospective analysis was done of deoxyribonucleic acid (...

Abstract

A 1.5cm. tubularized neourethra was formed using an anterior bladder flap as part of bladder neck reconstruction after radical retropubic prostatectomy in 69 consecutive patients with clinically localized prostate cancer (study group). ...

Abstract

In a Southwest Oncology Group phase II clinical trial, 68 patients with hormone refractory carcinoma of the prostate were treated with a combination of doxorubicin, mitomycin C and 5-fluorouracil. Of the patients 11 were classified as good risk ...

Abstract

To examine changing trends in the microbial etiology of nosocomial urinary tract infections, we reviewed culture data from a surveillance database for the calendar years 1982 to 1991. The overall rates of nosocomial urinary tract infections have ...

Abstract

The seminal vesicles can be approached laparoscopically and completely dissected free via the rectovesical cul-de-sac. This approach may be helpful during a perineal prostatectomy or when treating primary seminal vesicle pathological conditions.

Abstract

To calculate exit urine flow from the renal pelvis to the bladder in hydronephrosis, a simple method, radionuclide constant pressure perfusion study, was used. The mathematical model proposed for calculation of the exit flow (F) was simple: F = (...

Abstract

The effect of menthol on the human bladder cooling reflex was studied prospectively in a group of patients with a positive ice water test. Menthol has a selective potentiating action on cutaneous cold receptors and shifts the temperature response ...

Abstract

The physical difficulties associated with cystoscopy and cystometry in the spinal cord injury patient led to a clinical trial of synchronous cystoscopy and cystometry in these individuals. Following a disappointing experience with external ...

Abstract

Severe respiratory distress is the major cause of perinatal mortality associated with congenital urinary tract anomalies or severe obstructive uropathy, and is often accompanied by oligohydramnios. In the past the prognosis in these high risk ...

Abstract

We report on 30 consecutive patients (mean age 9 years) who underwent gastrocystoplasty (21) or received a continent urinary reservoir with stomach (9). A successful outcome, defined as complete urinary continence for intervals greater than 3hours,...

Abstract

We reviewed retrospectively 315 patients with bladder exstrophy treated at our hospital between July 1976 and April 1992 to assess the outcome of those who failed primary closure of the bladder. Of the patients 47 required reclosure of the bladder,...

Abstract

The response to desmopressin in 71 children with nocturnal enuresis was evaluated to determine whether a family history of nocturnal enuresis could be helpful in predicting which patients would respond. The overall response rate to desmopressin (...

Abstract

Cystourethrography in 25 children 0 to 13 years old demonstrated reflux of contrast material from the urethra or bladder into 1 or both ejaculatory ducts. The main findings observed in these patients are discussed and the literature is reviewed.

Abstract

We report on 24 patients with hypospadias and severe chordee that could not be straightened with conventional techniques. We used small dermal grafts to augment the ventral tunica albuginea, which resulted in a completely straight, normal ...

Abstract

Although juvenile xanthogranulomas are frequently seen by pediatricians and dermatologists, urological data are extremely rare. To our knowledge we report the first case of juvenile xanthogranuloma of the penis. Differentiation from other, similar ...

Abstract

We studied the usefulness of radiography for localization of cryptorchid testes. A total of 23 radiographic studies ordered by referring physicians was done for testis localization in 18 boys. Two patients had retractile testes and were followed ...

Abstract

Only 25% of boys with acute scrotal swelling have testicular torsion. A noninvasive test that reliably distinguishes torsed testes from all other acute scrotal conditions would benefit patients presenting with pain and swelling of the scrotum. ...

Abstract

Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression ...

Abstract

Bilateral spontaneous steinstrasse from the ureteropelvic junction to the distal ureter complicating distal renal tubular acidosis has not been described. We report a case and discuss the clinical presentation, radiographic and metabolic findings, ...

Abstract

A 70-year-old man with bilateral ureteroenteric anastomotic strictures and recurrent urinary tract sepsis that continued despite bilateral Double-J†Medical Engineering Corp., New York, New York. ureteral stents and nephrostomy tubes was ...

Abstract

Recurrent transitional cell carcinoma in a ureteroileal conduit following radical cystectomy is rare. The prognosis for these patients is uniformly poor. We report on a patient with transitional cell carcinoma in an ileal conduit treated by ...

Abstract

Primary plasmacytoma of the bladder is extremely rare, with only 10 cases reported in the literature. We report on a patient who was treated unsuccessfully with radiation and subsequently underwent anterior exenteration with ileo-conduit ...

Abstract

Priapism secondary to sickle cell anemia has been treated with a variety of therapeutic regimens. Recurrent sickle cell priapism is common and in many cases results when detumescence has not been achieved reliably. We report on a patient with ...

Abstract

A patient presented to our center with a 15-year history of medical, surgical and radiation treatment for a nonseminomatous germ cell tumor and contralateral seminoma. He experienced a cerebral infarction, which led to the diagnosis of an ...

Abstract

We performed extracorporeal shock wave lithotripsy with a Dornier HM3 lithotriptor to treat a distal ureteral calculus. Although the procedure resulted in successful stone fragmentation, the patient incurred a large scrotal hematoma. We propose a ...

Abstract

Idiopathic hematuria in the absence of bacteriuria is a medical challenge. Routine cultures of catheterized bladder and endoscopically obtained ureteral urine specimens from a 22-year-old woman with a 6-week history of hematuria showed no growth ...

Abstract

Forty-five stage A1 prostatic adenocarcinomas from patients with a mean age of 65 years were examined for p53 and c-myc expression to determine whether the presence or absence of these proteins could predict tumor behavior. Thirteen (6 of 45) and ...

Abstract

Endothelins mediate contractile responses in many types of vascular and nonvascular smooth muscle. The present study represents the first detailed characterization of endothelins in the human prostate. The objectives of this study were to ...

Abstract

The distribution of afferents innervating the urinary bladder in the spinal cord of male rats has been studied with the axonal tracer horseradish peroxidase conjugated to wheat germ agglutinin (WGA-HRP) injected into various portions of one side ...

Abstract

We evaluated multidrug resistance (MDR) in human bladder cancer cell lines UM-UC-2, UM-UC-6, UM-UC-9 and the UM-UC-6dox subline induced to doxorubicin resistance by in vitro doxorubicin exposure. We compared the profile of multidrug resistance in ...

Abstract

To evaluate the hypothesis that testicular descent is mediated by the action of high local concentrations of dihydrotestosterone in the gubernaculum, testis, or epididymis, we obtained tissues from 30 male pig fetuses between 63 and 101 days of ...

Abstract

We have studied the Major Histocompatibility Class II-modulating and antiproliferative actions of recombinant interferon-γ, tumor necrosis factor-α, interleukin-1α, interleukin-2 and granulocyte macrophage-colony stimulating factor on bladder ...

Abstract

The effects of the pharmacological changes of sympathetic innervation were studied in a rat model of electrically induced erection. Stimulation of the cavernous nerve elicited an erectile response measured by intracavernous pressure and separated ...

Abstract

Experimental studies in the therapy of intravesically growing bladder tumors in mice have been hampered by an inability to monitor tumor growth before and during treatment. To establish a repeatable, noninvasive method to monitor the intravesical ...

Abstract

Longitudinal smooth muscle strips taken from the urinary bladders of Sprague-Dawley rats, aged approximately 6 months and 24 months, were examined under a variety of conditions. Force development in response to electrical field stimulation and to ...

Abstract

The effects on micturition of the GABA receptor agonists muscimol (selective for GABA_A - receptors) and baclofen (selective for GABA_B-receptors), given intrathecally and intra-arterially to unanesthetized rats with and without bladder hypertrophy ...

Abstract

The rat urinary bladder responded to intravesical obstruction by an increased weight. The weight began to increase after 3 days of obstruction. After 10 days the weight gain had become significant, but increased further with time. At 90days the ...

Abstract

The dynamic component of bladder outlet obstruction caused by benign prostatic hyperplasia (BPH) is regulated by alpha₁ adrenergic receptors (α₁-AR) located in the prostatic stroma. Recently two α₁-AR subtypes (α_1A, α_1B) have been identified in ...