MP59-03 THULIUM LASER ENUCLEATION (ThuLEP) VERSUS TRANSURETHRAL BIPOLAR PROSTATE RESECTION (TURP): PROSPECTIVE RANDOMIZED STUDY: EARLY INTRA- AND POSTOPERATIVE RESULTS
Abstract
INTRODUCTION AND OBJECTIVE:
The aim is the comparison of early intra- and postoperative clinical results between transurethral enucleation of the prostate with thulium laser (ThuLEP) and transurethral bipolar resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia (BPH) in a prospective randomized trial.
METHODS:
In the study 650 consecutive patients with BPH were randomized: ThuLEP (n=350) and TURP (n=300). The parameters evaluated were: blood loss, catheterisation time, irrigation volume, hospital stay and operating time. At 6 months after surgery they were evaluated: International Prostate Symptom Score (IPSS), maximum flow (Qmax) and postmintional residue (RPM).
RESULTS:
Patients in each study arm did not show any significant differences in preoperative parameters compared to TURP, ThuLEP required the same operating time (53.69±31.44 vs 61.66±18.7 minutes, p=.123) but resulted in a reduction in lower hemoglobin values (0.45 vs 2.83 g/dL, p=0.005). ThuLEP also determined less non statistically significant catheterisation time, lower irrigation volume (29.4 vs 69.2 L, p=0.002) and lower non-significant hospital stay (1.7 vs 2.5 days). During the 6-month follow-up, procedures did not show a significant difference in Qmax, IPSS, PVR and Quality of life Scale (QOLS).
CONCLUSIONS:
ThuLEP and TURP reduce both symptoms of the lower urinary tract with efficacy and safety. ThuLEP is statistically superior to TURP in terms of blood loss, irrigation volume. However, procedures do not differ significantly in Qmax, IPSS, RPM and QOLS for up to 6 months of follow-up.
Source of Funding:
None