Erectile Dysfunction Risk Factors in Noninsulin Dependent Diabetic Saudi Patients
Abstract
Purpose:
We assessed the prevalence of and analyzed risk factors for erectile dysfunction in patients with noninsulin dependent diabetes in Makkah, Saudi Arabia.
Materials and Methods:
A total of 562 male diabetic Saudi patients were enrolled in this study. Patients were screened for erectile dysfunction using the International Index of Erectile Function. At the time of screening patients were also interviewed for sociodemographic data, including age, education, occupation, marital status and smoking. Medical history included diabetes, diabetes related complications, risk factors for diabetes and erectile dysfunction, and current medication.
Results:
Mean age of the study sample was 53.7 years (range 27 to 84). Of the patients 86.1% had various degrees of erectile dysfunction, including mild in 7.7%, moderate in 29.4% and severe in 49.1%. The prevalence of erectile dysfunction was 25% in patients younger than 50 years, which increased to 75% in those older than 50 years. Of those without erectile dysfunction 70% were younger and 30% were older than 50 years (p = 0.0001). Patients with a history of diabetes of greater than 10 years were 3 times as likely to report erectile dysfunction as those with a history of less than 5 years. Men with poor metabolic control were 12.2 times as likely to report erectile dysfunction as those with good metabolic control. Of diabetic patients with erectile dysfunction 53% had 1 or more diabetic related complications compared with 20.5% with no erectile dysfunction (p = 0.0001).
Conclusions:
Erectile dysfunction is common in diabetic Saudi men. This study provides a quantitative estimate of the prevalence of erectile dysfunction and its main risk factors in diabetic Saudi patients.
References
- 1 : Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol1994; 151: 54. Link, Google Scholar
- 2 : Sildenafil for treatment of erectile dysfunction in men with diabetes. A randomized controlled study. Sildenafil Diabetes Study Group. JAMA1999; 281: 421. Google Scholar
- 3 Statistical Abstract of the United States 1992. Washington, D.C.: United States Bureau of the Census1992: 19. Google Scholar
- 4 : Impotence in diabetic men. Mt Sinai J Med1987; 54: 236. Google Scholar
- 5 : Erectile dysfunction in general medicine practiaaa prevalence and clinical correlates. Int J Impot Res2000; 12: 41. Google Scholar
- 6 : Erectile dysfunction in type 1 and type 2 diabetics in Italy. On behalf of Gruppo Italiano Studio Deficit Erettilenei Diabetici. Int J Epidemiol2000; 29: 524. Google Scholar
- 7 : Diabetic penile neuropathy. Urol Clin North Am1988; 15: 17. Google Scholar
- 8 : Effects of diabetes on nitric oxide synthase and growth factor genes and protein expression in an animal model. Int J Impot Res1999; 11: 123. Google Scholar
- 9 : Diminished neurogenic but not pharmacological erections in the 2- to 3-month experimentally diabetic F-344 rat. Am J Physiol1997; 272: H1960. Google Scholar
- 10 NIH Consensus Conference Impotence. NIH Consensus Development Panel on Impotenaaa impotence. JAMA1993; 270: 83. Google Scholar
- 11 : Impotence and diabetes mellitus. JAMA1958; 168: 498. Google Scholar
- 12 : The natural history of impotence in diabetic men. Diabetologia1984; 26: 437. Google Scholar
- 13 : Traumatic arteriogenic erectile dysfunction: a rat model. Int J Impot Res2001; 13: 162. Google Scholar
- 14 : Radiation-associated impotence. A clinical study of its mechanism. JAMA1984; 251: 903. Crossref, Medline, Google Scholar
- 15 : Is impotence an arterial disorder? A study of arterial risk factors in 440 impotent men. Lancet1985; 1: 181. Crossref, Medline, Google Scholar
- 16 : Smoking habits of physicians in Riyadah, Saudi Arabia. Saudi Med J1989; 10: 508. Google Scholar
- 17 : Hypertension is associated with severe erectile dysfunction. J Urol2000; 164: 1188. Link, Google Scholar
- 18 : Prevalence of hypertension in adult Saudi population. Saudi Med J1998; 19: 117. Google Scholar
- 19 :
Potency problems in cardiac patients and arteriopaths . In: Impotenaaa Diagnosis and Management of Male Erectile Dysfunction. Edited by . Oxford: Butterworth-Heinemann Ltd1991: 232. Google Scholar - 20 : Relationship of penile brachial pressure index to myocardial infarction and cerebrovascular accidents in older men. Am J Med1988; 84: 445. Google Scholar
From the Department of Urology Suez Canal University, School of Medicine, Ismailia, Egypt and #Al-Noor Specialist Hospital, Diabetic Center, Makkah, Saudi Arabia
