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You have accessJournal of UrologySexual Function/Dysfunction: Medical, Hormonal & Non-surgical Therapy I1 Apr 2018

PD31-10 COMPARISON BETWEEN NANOTECHNOLOGY STRUCTURED WATER AND TADALAFIL FOR THE TREATMENT OF ERECTILE DYSFUNCTION.

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    INTRODUCTION AND OBJECTIVES

    Erectile dysfunction (ED) affects more than one-third of men and its prevalence increases with age especially in men over 40 years. Nanotechnology structured water is a new type of water that has been prepared using certain energy fields and modulators to produce this nano-water. In this study, we compared the efficacy of nano-water with Tadalafil, and with ordinary bottled water in the treatment of erectile dysfunction.

    METHODS

    For a period of 3 months, 271 men with ED were included in this clinical study. Inclusion criteria were diagnosed ED for at least 6 months with no contraindications for tadalafil and with no anatomical abnormalities as a cause of ED. Those men were randomly divided into three groups. Group A, given nanotechnology structured water magnalife in a daily dose of 20ml/Kg body weight, group B given daily dose of Tadalafil 5mg, and group C given ordinary bottled water in a daily dose of 20ml/Kg. The water bottles were unlabeled, both patients and investigators were blinded to the type of water used. The assessment of the ED degree and the success of treatment was done by International Index of Erectile Function–Erectile Function (IIEF-EF) domain (questions 1-5, and question 15), Sexual Encounter Profile question1 (SEP1) and (SEP2) and Global Assessment Question1 (GAQ1) and (GAQ2) related to erectile function. Those data were taken at the beginning (baseline data) and at the end of the 3 months.

    RESULTS

    In this study, 262 of 271 patients were followed for 3 months (9 men dropped out). Group A (n=87) had statistically significant improvements in IIEF-EF from 14.39 to 22.64 (P <0.001), positive response to SEP1 increased from 62% to 83% (P <0.001), SEP2 improved from 35% to 77% (P<0.001), also the GAQ1 was 85% (P <0.001) and GAQ2 was 79% (P <0.001). Group B (n=90), showed statistically significant improvements in IIEF-EF from 13.89 to 27.38 (P<0.001), SEP1 improved from 60 % to 89% (p<0.001) and SEP2 from 37% to 85% (P<0.001), also GAQ1 was 91% (P<0.001) and GAQ2 was 84% (P<0.001). But Group C (n=85) showed statistically non significant changes in IIEF-EF from 13.58 to 14.95 (P=0.021) and SEP1 from 65% to 64% (P=0.021) and SEP2 from 33 % to 35%(P=0.0215), also GAQ1was 16% and GAQ2 was 13%.

    CONCLUSIONS

    Nanotechnology structured water is a new modality to treat ED patients without the need for expensive medications with no reported side effects or contraindications for use in patients with cardiovascular diseases. However, further studies are needed to evaluate its long term effects and to see its safety in different types of patients.

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