We compare the safety, ease of use and effectiveness of the no scalpel and standard incision approaches to vasectomy.

Materials and Methods:

A multicenter, randomized, partially masked controlled trial was conducted at 8 sites in Brazil, Guatemala, Indonesia, Sri Lanka and Thailand. Semen samples were collected 10 weeks postoperatively and tested to ascertain sterility using verification of no living spermatozoa.


The study included 1,429 men seeking vasectomy. The efficacy of the 2 approaches was virtually identical. In the no scalpel group operating time was significantly shorter, and complications and pain were less frequent than in the standard incision group. The no scalpel group resumed intercourse sooner, probably as a result of less pain following the procedure.


The no scalpel approach is an important advance in the surgical approach to vasectomy, and offers fewer side effects and greater comfort compared to the standard incision technique, without compromising efficacy.


  • 1 : No-scalpel vasectomy. Sem. Urol.1992; 10: 252. Google Scholar
  • 2 : The no-scalpel vasectomy. J. Urol.1991; 145: 341. LinkGoogle Scholar
  • 3 : No-scalpel vasectomy at the King's birthday vasectomy festival. Lancet1990; 335: 894. Google Scholar
  • 4 : Minimally invasive vasectomy. Brit. J. Urol.1996; 77: 585. Google Scholar
  • 5 : Increasing the availability of vasectomy in public-sector clinics. Fam. Plan. Perspect.1997; 29: 185. Google Scholar
  • 6 : Clinical aspects of vasectomies performed in the United States in 1995. Urology1998; 52: 685. Google Scholar
  • 7 : Clinical efficacy trials with categorical data. In: . New York: Marcel Dekker1988. Google Scholar
  • 8 : Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer Inst.1959; 22: 719. Google Scholar
  • 9 StatXact 3 for Windows. Cambridge: Cytel Software Corporation1995. Google Scholar
  • 10 : The analysis of several 2 × 2 contingency tables. Biometrika1971; 58: 129. Google Scholar
  • 11 : . New York: John Wiley & Sons1980. Google Scholar
  • 12 : An improved approximate formula for calculating sample sizes for comparing 2 binomial distributions. Biometrics1978; 4: 483. Google Scholar
  • 13 : Results of a pilot study of the time to azoospermia after vasectomy in Mexico City. Contraception1997; 56: 215. Google Scholar

From the Family Health International and Clinical Trials Support Services, Research Triangle Park, North Carolina